Osteomyelitis with methicillin-resistant Staphylococcus aureus.

Abstract

We describe 10 patients with hospital-acquired osteomyelitis due to methicillin-resistant Staphylococcus aureus. The patients were posttraumatic and eight had a foreign body in situ at the site of infection. Vancomycin therapy in association with radical debridement was followed by clinical and radiological cure in eight patients at 2-3.5 years follow-up, in two of whom a foreign body was left in situ. Only minor adverse effects of vancomycin therapy (one rash, two thrombophlebitis) were seen.

• Authors: D J Fitzpatrick, M T Cafferkey, M Toner, T Beattie, C T Keane
• Journal: The Journal of hospital infection (J Hosp Infect) Vol. 8 Issue 1 Pg. 24-30 (Jul 1986) ISSN: 0195-6701 [Print] England
• PMID: 2875098 (Publication Type: Journal Article)

Chemical References

• Vancomycin
• Methicillin

Topics

• Adult
• Aged
• Child
• Cross Infection (microbiology, therapy)
• Debridement
• Female
• Fracture Fixation, Internal
• Fractures, Bone (complications)
• Humans
• Male
• Methicillin (pharmacology)
• Middle Aged
• Osteomyelitis (microbiology, therapy)
• Penicillin Resistance
• Staphylococcal Infections (therapy)
• Staphylococcus aureus (drug effects)
• Vancomycin (therapeutic use)