[Effectiveness and tolerance of metipranolol--results of a multi-center long-term study in Switzerland].

Abstract

The results of this continuing multicenter study revealed a good efficacy and tolerance of Metipranolol used in patients with ocular hypertension and chronic open-angle glaucoma. After 4 weeks' treatment a reduction in average intraocular pressure of 5.6 mmHg could be observed. This favorable effect on pressure values could be confirmed during long-term treatment up to 16 weeks (average reduction in intraocular pressure of 5.9 mmHg equal to 25%). More than 90% of patients treated with 0.1% Metipranolol showed very good or good tolerance. In conclusion, it can be established that 0.1% Metipranolol has also confirmed its value in daily practice and offers an interesting possibility for low-dosage beta-blocker therapy.

• Authors: O Müller, H R Knobel
• Journal: Klinische Monatsblatter fur Augenheilkunde (Klin Monbl Augenheilkd) Vol. 188 Issue 1 Pg. 62-3 (Jan 1986) ISSN: 0023-2165 [Print] Germany
• Vernacular Title: Wirksamkeit und Verträglichkeit von Metipranolol--Resultate einer multizentrischen Langzeitstudie in der Schweiz.
• PMID: 2870216 (Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)

Chemical References

• Propanolamines
• Metipranolol

Topics

• Clinical Trials as Topic
• Glaucoma, Open-Angle (drug therapy)
• Humans
• Intraocular Pressure (drug effects)
• Long-Term Care
• Metipranolol (adverse effects, therapeutic use)
• Ocular Hypertension (drug therapy)
• Propanolamines (therapeutic use)
• Switzerland