Agitation observed during treatment with newer hypnotic drugs.

Side effects involving agitation, e.g., sleepwalking, anger, and panic, were observed in 10 insomniac patients treated with temazepam or triazolam but not other benzodiazepines. Each patient described these side effects as uncharacteristic. Milder agitation was observed in 2 cases. In 4 cases, these effects were doubted by the prescribing physician. This type of side effect has been only slowly recognized for other benzodiazepines and has not been much reported for these newer agents. Agitation observed during treatment with these agents may be related to their short elimination half-lives.
AuthorsQ R Regestein, P Reich
JournalThe Journal of clinical psychiatry (J Clin Psychiatry) Vol. 46 Issue 7 Pg. 280-3 (Jul 1985) ISSN: 0160-6689 [Print] UNITED STATES
PMID2861195 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Anti-Anxiety Agents
  • Triazolam
  • Temazepam
  • Adult
  • Aged
  • Akathisia, Drug-Induced
  • Anger
  • Anti-Anxiety Agents (adverse effects, metabolism)
  • Female
  • Half-Life
  • Hostility
  • Humans
  • Male
  • Middle Aged
  • Panic
  • Psychomotor Agitation (psychology)
  • Sleep Initiation and Maintenance Disorders (drug therapy)
  • Somnambulism (chemically induced)
  • Temazepam (adverse effects)
  • Triazolam (adverse effects)

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