Clorazepate in the treatment of complex partial seizures with psychic symptomatology.

Abstract

Clorazepate frequently can control symptoms in complex partial seizure disorders with psychic symptomatology at dosages less than those recommended for its use as an adjunctive anticonvulsant. Four case examples illustrate this use. These beneficial effects may reflect a heightened response by limbic seizure foci to the anticonvulsant effects of nordiazepam, or a potentiation of its anticonvulsant effects through attenuating patient anxiety.

• Authors: J L Griffith, G B Murray
• Journal: The Journal of nervous and mental disease (J Nerv Ment Dis) Vol. 173 Issue 3 Pg. 185-6 (Mar 1985) ISSN: 0022-3018 [Print] United States
• PMID: 2857765 (Publication Type: Journal Article)

Chemical References

• Anti-Anxiety Agents
• Anticonvulsants
• Clorazepate Dipotassium

Topics

• Adult
• Anti-Anxiety Agents (therapeutic use)
• Anticonvulsants (therapeutic use)
• Anxiety (drug effects)
• Clorazepate Dipotassium (administration & dosage, pharmacology, therapeutic use)
• Delusions (drug therapy, psychology)
• Dose-Response Relationship, Drug
• Drug Therapy, Combination
• Epilepsy, Temporal Lobe (drug therapy, physiopathology, psychology)
• Female
• Hallucinations (drug therapy, psychology)
• Humans
• Limbic System (drug effects, physiopathology)
• Male
• Paranoid Disorders (drug therapy, psychology)