Abstract | BACKGROUND: OBJECTIVE: METHODS: This was a cross-sectional study performed in 30,068 participants (mean age 40.8 years; 84.5% men) in a health screening program in Korea. The data were collected from 2001 to 2013 and analyzed in 2015. Total energy intake and dietary cholesterol intake were assessed with a food frequency questionnaire. The participants were stratified according to quartile of dietary cholesterol intake. CACS was measured by multi-detector computed tomography. Lipid profiles were measured, and the participants were divided into 6 groups according to low-density lipoprotein cholesterol ( LDL-C) level: <70, 70 to 99, 100 to 129, 130 to 159, 160 to 189, and ≥190 mg/dL. RESULTS: The presence of coronary artery calcification was defined as CACS>0. Dietary cholesterol intake did not correlate with mean value of serum LDL-C level. For both genders, the odds ratio for coronary artery calcification was not significantly greater with greater amounts of dietary cholesterol (as assessed by quartile). The risk for coronary artery calcification was not higher in subjects with LDL-C 70-129 mg/dL compared with those with LDL-C < 70 mg/dL; however, the risk was significantly greater in subjects with LDL-C ≥ 130 mg/dL compared with those with LDL-C < 70 mg/dL. CONCLUSIONS:
Dietary cholesterol intake did not have an association with LDL-C level or with risk for coronary artery calcification in apparently healthy Korean adults. The results have to be translated with consideration of limitation of population-based studies.
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Authors | Eun-Jung Rhee, Seungho Ryu, Jong-Young Lee, Sung Ho Lee, EunSun Cheong, Se Eun Park, Cheol-Young Park, Yu Sam Won, Joon Mo Kim, Dong-Sik Cho, Hye-Kyung Chung, Ki Chul Sung |
Journal | Journal of clinical lipidology
(J Clin Lipidol)
2017 Mar - Apr
Vol. 11
Issue 2
Pg. 432-441.e3
ISSN: 1933-2874 [Print] United States |
PMID | 28502500
(Publication Type: Journal Article)
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Copyright | Copyright © 2017 National Lipid Association. Published by Elsevier Inc. All rights reserved. |
Chemical References |
- Cholesterol, Dietary
- Cholesterol, LDL
- Calcium
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Topics |
- Adult
- Atherosclerosis
(blood, epidemiology, metabolism)
- Calcium
(metabolism)
- Cholesterol, Dietary
(pharmacology)
- Cholesterol, LDL
(blood)
- Coronary Vessels
(drug effects, metabolism)
- Cross-Sectional Studies
- Female
- Health Surveys
- Humans
- Male
- Republic of Korea
(epidemiology)
- Risk
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