Successful Treatment of Stable Vitiligo by Low-Density Cultured Autologous Melanocyte Transplantation Combined With Narrowband Ultraviolet B Therapy.

Abstract

BACKGROUND:

Cultured autologous melanocyte transplantation (CMT) is an effective treatment for stable vitiligo, but the current method is time consuming and expensive because of the requirement of a large number of melanocytes.

OBJECTIVE:

To assess the clinical effect of low-density CMT combined with narrowband ultraviolet B (NB-UVB) in treating stable vitiligo.

MATERIALS AND METHODS:

The authors treated 8 patients with CMT at a low cell density (less than 2.5 × 10 cells/cm). Among them, 6 patients underwent NB-UVB therapy after CMT.

RESULTS:

All the 6 patients treated with low-density CMT combined with NB-UVB obtained more than 90% repigmentation at the 1-year follow-up.

CONCLUSION:

The authors' data suggest that low-density CMT combined with NB-UVB can be an effective form of surgical treatment for stable vitiligo.

• Authors: Lei Yao, Yuanyuan Liu, Yang Song, Shuxia Zhong, Shanshan Li
• Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 43 Issue 10 Pg. 1281-1287 (Oct 2017) ISSN: 1524-4725 [Electronic] United States
• PMID: 28445194 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Child
• Combined Modality Therapy
• Female
• Humans
• Male
• Melanocytes (transplantation)
• Remission Induction
• Transplantation, Autologous
• Ultraviolet Therapy
• Vitiligo (radiotherapy, surgery)
• Young Adult