Clinical trials examining
targeted temperature management in children support avoidance of
hyperthermia for both pediatric in-hospital
cardiac arrest (
PIHCA) and
out-of-hospital cardiac arrest (POHCA), but no statistically significant outcome differences were confirmed comparing 33 and 36 °C in the limited populations studied. Retrospective analyses of population-based POHCA registries revealed several associations: both bystander
CPR and public-access defibrillation were associated with improved POHCA outcomes; conflicting results overshadow the benefits of conventional versus compression-only
CPR; extracorporeal
CPR was associated with improved
PIHCA outcomes regardless of cause; intubation in
PIHCA was associated with decreased survival, whereas there were no significant differences in outcomes between advanced
airway management and bag-valve-mask ventilation in POHCA; and early
epinephrine delivery in nonshockable rhythms during
PIHCA was associated with improved outcomes. Length, age, and weight-based dosing systems can reduce time to medication delivery, quantitative errors, and anxiety among care providers.
SUMMARY: