[A case of primary hepatoma with marked reduction of the tumor after oral administration of tegafur].

Abstract

A 57-year-old male complaining mainly of pain in the right terminal rib area was admitted to hospital for hepatic tumor examination. Primary hepatoma with infiltration of the inferior vena cava was diagnosed by various imaging techniques and the subject was started on a program of daily oral administrations of 800 mg of tegafur. Prior to commencing drug administration the hepatic tumor measured 112 x 80 mm; after four months of treatment the tumor was reduced to 56 x 48 mm and the infiltration in the inferior vena cava had disappeared. The tumor continued to decrease in size thereafter, and today measures 32 x 28 mm after three years of tegafur administration. The subject continues to be monitored as an outpatient. A marked reduction in the size of a hepatic tumor was observed in this case, and the administration of tegafur has proved effective in prolonging life for over three years.

• Authors: T Kitamura, T Maruyama, M Shigehira, J Ishizaki, K Hayashi, H Nakamura, K Tsuda
• Journal: Gan to kagaku ryoho. Cancer & chemotherapy (Gan To Kagaku Ryoho) Vol. 15 Issue 2 Pg. 349-52 (Feb 1988) ISSN: 0385-0684 [Print] Japan
• PMID: 2829747 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Tegafur

Topics

• Administration, Oral
• Carcinoma, Hepatocellular (drug therapy)
• Drug Administration Schedule
• Humans
• Liver Neoplasms (drug therapy)
• Male
• Middle Aged
• Remission Induction
• Tegafur (administration & dosage)