[Hemophilic arthropathies. Apropos of 51 cases].

After defining the clinical, roentgenological and anatomic features of the various kinds of hemophilia-related joint disease (acute hemarthrosis, subacute arthritis, and chronic joint disease), we present a study of outcomes in fifty-one hemophiliac children aged 0 to 15 years and followed-up from January 1968 through December 1987 at the Angers Regional University Hospital. Four hundred and sixty-four cases of hemarthrosis were seen. Risk factors for hemarthrosis were severe hemophilia and age between 5 and 15 years, and the joints most often involved were the ankles, knees, and elbows. Sequelae of hemarthrosis were extremely prevalent in this study population: 100% of patients with severe hemophilia and 90% of patients with a factor activity of 3% or less exhibited chronic joint disease by the age of fifteen, with varying degrees of functional impairment. Because a first episode of hemarthrosis is often followed by recurrences in the same joint, we underline the need for prevention and careful treatment of acute episodes, which are the only means for decreasing articular sequelae.
AuthorsO Minckes, X Rialland, F Laumonnier, E Fressinaud, J P Atanasiu, L Larget-Piet
JournalAnnales de peĢdiatrie (Ann Pediatr (Paris)) Vol. 36 Issue 7 Pg. 425-34 (Sep 1989) ISSN: 0066-2097 [Print] FRANCE
Vernacular TitleArthropathies hémophiliques. A propos de cinquante et un cas.
PMID2817697 (Publication Type: English Abstract, Journal Article)
  • Acute Disease
  • Adolescent
  • Age Factors
  • Child
  • Child, Preschool
  • Chronic Disease
  • Hemarthrosis (epidemiology, etiology)
  • Hemophilia A (complications)
  • Humans
  • Infant
  • Infant, Newborn
  • Recurrence
  • Severity of Illness Index

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