Abstract |
Urine- Tissue Polypeptide Antigen (U-TPA) was measured in 81 patients with a previously diagnosed bladder carcinoma. U-TPA was elevated in 74% of the patients with invasive bladder cancer as compared to only 15% of the patients with superficial tumors. Only one patient without a tumor recurrence had an elevated U-TPA level (4%). The results were compared with cytological grading and flow- DNA measurements in a multivariate analysis with T-category as the result variable. U-TPA and grade showed each, independently, a significant relation (P much less than 0.001) to T-category whereas the result of the DNA measurements did not explain the variation in T-category when U-TPA and grade were already in the equation. For diagnostic purposes U-TPA seems to be of limited value but may serve as an indicator of tumor recurrence in bladder cancer patients.
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Authors | B E Carbin, P Ekman, P Eneroth, B Nilsson |
Journal | Urological research
(Urol Res)
Vol. 17
Issue 5
Pg. 269-72
( 1989)
ISSN: 0300-5623 [Print] Germany |
PMID | 2815427
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Antigens, Neoplasm
- Biomarkers, Tumor
- Peptides
- Tissue Polypeptide Antigen
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Topics |
- Antigens, Neoplasm
(urine)
- Biomarkers, Tumor
(urine)
- Carcinoma, Transitional Cell
(immunology)
- Flow Cytometry
- Humans
- Neoplasm Recurrence, Local
(immunology)
- Peptides
(urine)
- Tissue Polypeptide Antigen
- Urinary Bladder Neoplasms
(immunology)
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