Calvarial bone regeneration using osteogenin.

Abstract

This experimental study reports on the application of a partially purified noncollagenous protein extracted from cortical bone to restore craniotomy defects in Papio species (baboon). The partially purified protein (osteogenin) produced significantly more bone formation in calvarial wounds than was found in the untreated controls. There were no adverse tissue reactions from the implanted xenogeneic osteogenin.

• Authors: J Hollinger, D E Mark, D E Bach, A H Reddi, A E Seyfer
• Journal: Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons (J Oral Maxillofac Surg) Vol. 47 Issue 11 Pg. 1182-6; discussion 1187 (Nov 1989) ISSN: 0278-2391 [Print] United States
• PMID: 2809833 (Publication Type: Journal Article)

Chemical References

• Capsules
• Growth Substances

Topics

• Animals
• Bone Matrix
• Bone Regeneration (drug effects)
• Capsules
• Female
• Growth Substances (pharmacology)
• Male
• Papio
• Skull (drug effects, metabolism)