Detection of glucose intolerance in pregnancy.

Abstract

Between 6 and 28 weeks of gestation, 2-hour postprandial blood glucose determinations were performed on 66 pregnant patients who had no history of diabetes. Each patient received two methods of carbohydrate loading on separate occasions in a random, crossover fashion. One group received a 100-g carbohydrate meal and then a 50-g glucose load (Glucola). The order of the test regimens was reversed for the second group. The average 2-hour postprandial glucose value following a meal was 103.1 +/- 3.7 mg/dL, and the mean value for the 2-hour postprandial glucose following Glucola was 102.5 +/- 3.8 mg/dL. The difference in glucose values obtained with the two methods was not statistically significant. A 12% incidence of emesis was encountered after Glucola but none was encountered after the meal. The 100-g carbohydrate meal is recommended as the method of testing for glucose intolerance.

• Authors: D G Helton, R W Martin, J N Martin Jr, G R Meeks, J C Morrison
• Journal: Journal of perinatology : official journal of the California Perinatal Association (J Perinatol) Vol. 9 Issue 3 Pg. 259-61 (Sep 1989) ISSN: 0743-8346 [Print] United States
• PMID: 2809777 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)

Chemical References

• Blood Glucose

Topics

• Adolescent
• Adult
• Blood Glucose (analysis)
• Evaluation Studies as Topic
• Female
• Glucose Tolerance Test (methods)
• Humans
• Pregnancy
• Pregnancy in Diabetics (blood, diagnosis)
• Random Allocation