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[A case report of graft-versus-host reaction after aortocoronary bypass--a clinicopathological study].

Abstract
An immunologically normal 70-year-old male developed fever and disturbance of consciousness after aortocoronary bypass; this was followed by diarrhea, systemic erythroderma and granulocytopenia. He died as a result of sepsis and acute renal failure. The skin biopsy showed basel vacuolar degeneration, epidermal eosinophilic necrosis and invasion of T-lymphocytes. The autopsy showed necrotic small interlobular bile ducts, severely hypoplastic bone marrow and widespread necrosis of lymphoid tissue. Based on these clinicopathological findings, we made a diagnosis of graft-versus host reaction after transfusion.
AuthorsT Souma, S Tsuchida, S Otani, M Kojima, R Tsunoda
Journal[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai (Nihon Kyobu Geka Gakkai Zasshi) Vol. 37 Issue 6 Pg. 1257-61 (Jun 1989) ISSN: 0369-4739 [Print] Japan
PMID2809302 (Publication Type: Case Reports, Journal Article)
Topics
  • Aged
  • Biopsy
  • Coronary Artery Bypass
  • Graft vs Host Disease (pathology)
  • Humans
  • Male
  • Postoperative Complications (pathology)
  • Skin (pathology)
  • Transfusion Reaction

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