Abstract |
An immunologically normal 70-year-old male developed fever and disturbance of consciousness after aortocoronary bypass; this was followed by diarrhea, systemic erythroderma and granulocytopenia. He died as a result of sepsis and acute renal failure. The skin biopsy showed basel vacuolar degeneration, epidermal eosinophilic necrosis and invasion of T-lymphocytes. The autopsy showed necrotic small interlobular bile ducts, severely hypoplastic bone marrow and widespread necrosis of lymphoid tissue. Based on these clinicopathological findings, we made a diagnosis of graft-versus host reaction after transfusion.
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Authors | T Souma, S Tsuchida, S Otani, M Kojima, R Tsunoda |
Journal | [Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
(Nihon Kyobu Geka Gakkai Zasshi)
Vol. 37
Issue 6
Pg. 1257-61
(Jun 1989)
ISSN: 0369-4739 [Print] Japan |
PMID | 2809302
(Publication Type: Case Reports, Journal Article)
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Topics |
- Aged
- Biopsy
- Coronary Artery Bypass
- Graft vs Host Disease
(pathology)
- Humans
- Male
- Postoperative Complications
(pathology)
- Skin
(pathology)
- Transfusion Reaction
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