Abstract |
Serum concentrations of iodine were determined after cattle were given ethylenediamine dihydriodide (EDDI) orally at dosages ranging from 0.0 (placebo) to 0.77 mg/kg of body weight/day. The serum iodine concentration was correlated with the dosage of EDDI. A rate of 0.11 mg EDDI/kg/day was correlated with serum iodine concentrations (20 to 80 micrograms/dl) previously found to be effective in preventing foot rot in cattle. A linear dose-response curve that was generated could be helpful in predicting dosage of EDDI if the serum iodine concentration is known.
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Authors | J Maas, J N Berg, R G Petersen |
Journal | American journal of veterinary research
(Am J Vet Res)
Vol. 50
Issue 10
Pg. 1758-9
(Oct 1989)
ISSN: 0002-9645 [Print] United States |
PMID | 2802309
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Ethylenediamines
- ethylenediamine
- Iodine
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Topics |
- Administration, Oral
- Animals
- Cattle
(metabolism)
- Dose-Response Relationship, Drug
- Ethylenediamines
(administration & dosage, pharmacokinetics)
- Female
- Iodine
(blood)
- Male
- Regression Analysis
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