[Laboratory and clinical investigations of cefodizime in infectious diseases in childhood].

Abstract

In this study, cefodizime (CDZM, THR-221) was administered to 34 children with infections and the efficacy was evaluated in 30 patients. The efficacy rate was 90.0% and CDZM was proved to be a highly effective antibiotic for infectious diseases in childhood. We also demonstrated that CDZM had strong antibacterial activities against both Gram-positive and Gram-negative bacteria. No severe toxicity related to intravenous injection of CDZM was observed in our 34 cases.

• Authors: Y Komada, S Arai, H Kamiya, M Sakurai, S Shimizu, H Nishi, M Inoue, M Kojima, H Kawaguchi, T Yoshizumi
• Journal: The Japanese journal of antibiotics (Jpn J Antibiot) Vol. 42 Issue 6 Pg. 1346-57 (Jun 1989) ISSN: 0368-2781 [Print] Japan
• PMID: 2795858 (Publication Type: English Abstract, Journal Article)

Chemical References

• Cefotaxime
• cefodizime

Topics

• Age Factors
• Bacteria (drug effects, isolation & purification)
• Bacterial Infections (drug therapy, metabolism, microbiology)
• Cefotaxime (analogs & derivatives, pharmacokinetics, pharmacology, therapeutic use)
• Child
• Child, Preschool
• Drug Evaluation
• Drug Resistance, Microbial
• Female
• Humans
• Infant
• Male
• Respiratory Tract Infections (drug therapy, metabolism, microbiology)