Ability of mini-implant-facilitated micro-osteoperforations to accelerate tooth movement in rats.

Abstract

INTRODUCTION:

Although current techniques for accelerated tooth movement often involve invasive surgical procedures, micro-osteoperforations (MOPs) using mini-implants may facilitate orthodontic tooth movement without raising flaps, reduce surgical risks, and increase patient acceptance. In this study, we evaluated the effectiveness of mini-implant-facilitated MOPs in inducing accelerated tooth movement and investigated the potential risks for root resorption.

METHODS:

Five MOPs were placed on the left side around the maxillary first molars in 6 rats using an automated mini-implant driver, whereas the right side received no MOPs as the control. Closed-coiled springs were secured from incisors to first molars for orthodontic tooth movement. Tooth movement was measured, and samples underwent radiologic and histologic analyses.

RESULTS:

The MOP side exhibited a 1.86-fold increase in the rate of tooth movement with decreased bone density and bone volume around the first molars compared with the control side. Hematoxylin and eosin and tartrate-resistant acid phosphatase analyses showed increased numbers of osteoclasts as well as new bone formation. Three-dimensional volumetric analysis of all 5 roots of the maxillary first molars demonstrated no statistically significant difference in root volumes.

CONCLUSIONS:

Mini-implant-facilitated MOPs accelerated tooth movement without increased risk for root resorption and therefore may become a readily available and efficient treatment option to shorten orthodontic treatment time with improved patient acceptance.

• Authors: Tracy Cheung, Juyoung Park, Deborah Lee, Catherine Kim, Jeffrey Olson, Shadi Javadi, Gregory Lawson, James McCabe, Won Moon, Kang Ting, Christine Hong
• Journal: American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics (Am J Orthod Dentofacial Orthop) Vol. 150 Issue 6 Pg. 958-967 (Dec 2016) ISSN: 1097-6752 [Electronic] United States
• PMID: 27894545 (Publication Type: Journal Article)
• Copyright: Copyright © 2016 American Association of Orthodontists. Published by Elsevier Inc. All rights reserved.

Topics

• Animals
• Male
• Mandible (diagnostic imaging, surgery)
• Molar (diagnostic imaging, surgery)
• Orthodontic Wires
• Rats
• Rats, Sprague-Dawley
• Root Resorption (diagnostic imaging, etiology)
• Tooth Movement Techniques (instrumentation, methods)
• X-Ray Microtomography