[Parathyroidectomy in children with renal failure. Retrospective study of 17 cases].

Abstract

Parathyroidectomy (PTX) is rarely needed in children with end-stage renal disease and the new forms of vitamin D decrease its frequency. We report 17 cases of patients (14 with dialysis and 3 with functional renal graft) suffering from renal insufficiency in the pediatric age group who required a PTX. The surgical indications and techniques (partial PTX, total PTX with or without graft) varied with time and circumstances. After partial PTX, 3/10 patients were reoperated on. After PTX + graft one patient needed a second graft and another a graft curettage. Whatever the method, we noted normalization of clinical and radiological signs and a decrease in biological signs. The growth rate improved in most children during puberty, but outside of this period, no effect was noted. There is a definite indication for a PTX in cases with tertiary hyperparathyroidism. The indication seems questionable in cases with secondary hyperparathyroidism which can now be effectively treated with 1 alpha-hydroxylated forms of vitamin D. When necessary, total PTX with or without graft should be performed.

• Authors: E Bérard, G Crosca, M Broyer, C Fekete, M Kenesi, M Dechaux
• Journal: Archives francaises de pediatrie (Arch Fr Pediatr) 1989 Jun-Jul Vol. 46 Issue 6 Pg. 417-24 ISSN: 0003-9764 [Print] France
• Vernacular Title: Parathyroïdectomie chez l'enfant insuffisant rénal. Etude rétrospective de 17 observations.
• PMID: 2783002 (Publication Type: English Abstract, Journal Article)

Topics

• Adolescent
• Adult
• Child
• Child, Preschool
• Female
• Follow-Up Studies
• Growth
• Humans
• Hyperparathyroidism, Secondary (surgery)
• Kidney Failure, Chronic (complications)
• Male
• Parathyroid Glands (pathology, surgery)
• Postoperative Period
• Retrospective Studies