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Addisonian crisis induced by treatment with rifampicin.

Abstract
A patient with spinal tuberculosis and subclinical adrenal tuberculosis who developed acute Addisonian crisis on starting anti-tuberculosis therapy including rifampicin is reported. The possibility that many patients with tuberculosis have adrenal involvement with limited hormonal reserve and that they may develop incipient adrenal failure on commencing treatment is discussed.
AuthorsE G Wilkins, E Hnizdo, A Cope
JournalTubercle (Tubercle) Vol. 70 Issue 1 Pg. 69-73 (Mar 1989) ISSN: 0041-3879 [Print] Scotland
PMID2781613 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antitubercular Agents
  • Rifampin
Topics
  • Addison Disease (chemically induced)
  • Adrenal Gland Diseases (complications)
  • Antitubercular Agents (therapeutic use)
  • Humans
  • Male
  • Middle Aged
  • Rifampin (adverse effects)
  • Tuberculosis, Endocrine (complications)
  • Tuberculosis, Spinal (complications)

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