| Abstract | Forty-three cases of male breast cancer treated in the past 3 decades, comprising 1.92% of total cases of breast cancer in both sexes during the same period, were analyzed. Local skin involvement occurred in half of the patients. 67.7% of the patients presented axillary lymph node metastases and 82.9% were in stage II and III. Non-infiltrative and infiltrative specific cancers were diagnosed in 2 cases each, and infiltrative non-specific in 39 cases. Retrospective determination of estrogen receptor (ER) and carcinoembryonic antigen (CEA) in 33 specimens revealed positive ER in 57.6% and positive CEA in 72.7%. The more advanced the clinical stage, the higher is the positive rate of ER. Cases with positive CEA usually carried a more invasive process and a poorer prognosis. Immunohistochemical investigation in male breast cancer patients was valuable in the selection of post-operative adjuvant endocrine therapy or chemotherapy. Postoperative rise in serum CEA in patients with positive CEA may indicate recurrence. |
| Authors | R N Xu |
| Journal | Zhonghua wai ke za zhi [Chinese journal of surgery]
(Zhonghua Wai Ke Za Zhi)
Vol. 27
Issue 1
Pg. 28-30, 61
(Jan 1989)
ISSN: 0529-5815 CHINA |
| PMID | 2776523
(Publication Type: English Abstract, Journal Article)
|
| Chemical References |
- Carcinoembryonic Antigen
- Receptors, Estrogen
|
| Topics |
- Adult
- Aged
- Aged, 80 and over
- Breast Neoplasms
(metabolism, pathology)
- Carcinoembryonic Antigen
(analysis)
- Carcinoma
(metabolism, pathology)
- Humans
- Immunohistochemistry
- Lymphatic Metastasis
- Male
- Middle Aged
- Receptors, Estrogen
(analysis)
- Retrospective Studies
|
