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Antimicrobial agents and dental caries in the rat.

Abstract
Two rat plaque-caries studies indicated that a 0.2% chlorhexidine solution topically applied to rat teeth was effective in reducing dental plaque. This reduction in plaque was accompanied by marked reductions in smooth surface caries, but not in sulcal lesions.
AuthorsJ L McDonald, G K Stookey
JournalJournal of dental research (J Dent Res) Vol. 57 Issue 2 Pg. 349-54 (Feb 1978) ISSN: 0022-0345 [Print] UNITED STATES
PMID277534 (Publication Type: Journal Article)
Chemical References
  • Biguanides
  • Pyridinium Compounds
  • Quaternary Ammonium Compounds
  • Cetylpyridinium
  • Chlorhexidine
Topics
  • Animals
  • Biguanides (therapeutic use)
  • Cetylpyridinium (therapeutic use)
  • Chlorhexidine (therapeutic use)
  • Dental Caries (pathology, prevention & control)
  • Dental Plaque (prevention & control)
  • Female
  • Pyridinium Compounds (therapeutic use)
  • Quaternary Ammonium Compounds (therapeutic use)
  • Rats

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