Abstract |
With a view to assess the efficacy of intrathecal pentazocine for post-operative pain relief, 60 patients randomly divided into 6 equal groups were administered graded doses (0, 1, 2, 3, 4 and 5 mg respectively) of pentazocine lactate, intrathecally along with 1 per cent bupivacaine. The duration of analgesia was found to be dose related till 3 mg. Higher doses did not increase the duration of analgesia nor were any untoward effects observed. It is concluded that intrathecal pentazocine is safe and effective for post-operative pain relief and 3 mg is the minimum effective dose without side effect.
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Authors | R Chawla, M K Arora, R Saksena, G R Gode |
Journal | The Indian journal of medical research
(Indian J Med Res)
Vol. 90
Pg. 220-3
(Jun 1989)
ISSN: 0971-5916 [Print] India |
PMID | 2767747
(Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
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Chemical References |
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Topics |
- Adolescent
- Adult
- Aged
- Dose-Response Relationship, Drug
- Humans
- Injections, Spinal
- Middle Aged
- Pain, Postoperative
(drug therapy)
- Pentazocine
(administration & dosage, therapeutic use)
- Time Factors
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