HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Efficacy & dose-response of intrathecal pentazocine for post-operative pain relief.

Abstract
With a view to assess the efficacy of intrathecal pentazocine for post-operative pain relief, 60 patients randomly divided into 6 equal groups were administered graded doses (0, 1, 2, 3, 4 and 5 mg respectively) of pentazocine lactate, intrathecally along with 1 per cent bupivacaine. The duration of analgesia was found to be dose related till 3 mg. Higher doses did not increase the duration of analgesia nor were any untoward effects observed. It is concluded that intrathecal pentazocine is safe and effective for post-operative pain relief and 3 mg is the minimum effective dose without side effect.
AuthorsR Chawla, M K Arora, R Saksena, G R Gode
JournalThe Indian journal of medical research (Indian J Med Res) Vol. 90 Pg. 220-3 (Jun 1989) ISSN: 0971-5916 [Print] India
PMID2767747 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Pentazocine
Topics
  • Adolescent
  • Adult
  • Aged
  • Dose-Response Relationship, Drug
  • Humans
  • Injections, Spinal
  • Middle Aged
  • Pain, Postoperative (drug therapy)
  • Pentazocine (administration & dosage, therapeutic use)
  • Time Factors

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: