Abstract |
The toxic effects of CDDP, erroneously given at 450 mg/sq m, are described. Life threatening gastrointestinal and myelotoxicity was observed as well as prolonged severe renal tubular acidosis without renal failure. No significant oto (brain-stem evoked responses) or neurotoxicity (EEG, neurologic examination and nerve conduction velocity) was detected indicating major age-related differences in the toxicity of this drug.
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Authors | R Haupt, G Perin, S Dallorso, M L Garré, A Sobrero |
Journal | Anticancer research
(Anticancer Res)
1989 Mar-Apr
Vol. 9
Issue 2
Pg. 427-8
ISSN: 0250-7005 [Print] Greece |
PMID | 2751267
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Cisplatin
(poisoning, toxicity)
- Dose-Response Relationship, Drug
- Humans
- Infant
- Rhabdomyosarcoma
(drug therapy)
|