A case of non-paraneoplastic anti-N-methyl d-aspartate receptor encephalitis presenting as a neuropsychiatric disorder.

Abstract

N-methyl d-aspartate receptor antibody encephalitis can often be a paraneoplastic manifestation of occult malignancy such as ovarian teratoma and rarely teratoma of mediastinum or testis and small cell lung carcinoma. We report a case of non-paraneoplastic anti-N-methyl d-aspartate receptor antibody-positive autoimmune encephalitis in a young patient who presented with neuropsychiatric features and made a very good recovery following treatment with intravenous immunoglobulin and steroids. The case highlights the need for increased vigilance for the condition in young females with or without a previous psychiatric history and emphasises the need for a multidisciplinary approach in the management of this challenging disorder with a good prognosis.

• Authors: Bindu Yoga, Marek Kunc, Fayyaz Ahmed
• Journal: SAGE open medical case reports (SAGE Open Med Case Rep) Vol. 2 Pg. 2050313X14558902 ( 2014) ISSN: 2050-313X [Print] England
• PMID: 27489663 (Publication Type: Case Reports)