Abstract |
Discussed is a case of a giant cell carcinoma that presented a high value of serum thyroglobulin. Histopathologically, this tumor had been diagnosed as being an anaplastic carcinoma that had transformed from a differentiated carcinoma, with calcification that was thought to have occurred from a preceding adenoma. To study the possibility of a malignant transformation, an immunohistochemical study of a specimen confirmed the production of thyroglobulin and vimentin, though the specimen stained negatively for keratin.
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Authors | N Murakami, Y Kawaura, M Sasaki, Y Munemoto, T Iwa, A Nonomura |
Journal | Gan no rinsho. Japan journal of cancer clinics
(Gan No Rinsho)
Vol. 35
Issue 8
Pg. 927-32
(Jul 1989)
ISSN: 0021-4949 [Print] Japan |
PMID | 2746867
(Publication Type: Case Reports, English Abstract, Journal Article)
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Chemical References |
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Topics |
- Aged
- Calcinosis
(pathology)
- Carcinoma
(blood, metabolism, pathology)
- Female
- Humans
- Immunohistochemistry
- Thyroglobulin
(biosynthesis, blood)
- Thyroid Neoplasms
(blood, metabolism, pathology)
- Vimentin
(biosynthesis)
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