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[A case report of a giant cell carcinoma of the thyroid].

Abstract
Discussed is a case of a giant cell carcinoma that presented a high value of serum thyroglobulin. Histopathologically, this tumor had been diagnosed as being an anaplastic carcinoma that had transformed from a differentiated carcinoma, with calcification that was thought to have occurred from a preceding adenoma. To study the possibility of a malignant transformation, an immunohistochemical study of a specimen confirmed the production of thyroglobulin and vimentin, though the specimen stained negatively for keratin.
AuthorsN Murakami, Y Kawaura, M Sasaki, Y Munemoto, T Iwa, A Nonomura
JournalGan no rinsho. Japan journal of cancer clinics (Gan No Rinsho) Vol. 35 Issue 8 Pg. 927-32 (Jul 1989) ISSN: 0021-4949 [Print] Japan
PMID2746867 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Vimentin
  • Thyroglobulin
Topics
  • Aged
  • Calcinosis (pathology)
  • Carcinoma (blood, metabolism, pathology)
  • Female
  • Humans
  • Immunohistochemistry
  • Thyroglobulin (biosynthesis, blood)
  • Thyroid Neoplasms (blood, metabolism, pathology)
  • Vimentin (biosynthesis)

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