HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Antibiotic therapy for cat-scratch disease?

Abstract
Cat-scratch disease is usually a benign, self-limited disease that causes regional lymphadenopathy. Occasionally, it may present with systemic symptoms and have a prolonged course. To date, antibiotic therapy has not been proved to be of value. We describe three patients with cat-scratch disease who were treated successfully with gentamicin sulfate. Two patients had extensive hepatic involvement, and one patient had regional lymphadenopathy. All three patients responded within 48 hours to intravenous gentamicin. Extensive follow-up has shown no recurrence of symptoms. These cases suggest that gentamicin may be efficacious in shortening the course of cat-scratch disease. Prospective, randomized trials should be performed to confirm these results.
AuthorsC W Bogue, J D Wise, G F Gray, K M Edwards
JournalJAMA (JAMA) Vol. 262 Issue 6 Pg. 813-6 (Aug 11 1989) ISSN: 0098-7484 [Print] United States
PMID2746837 (Publication Type: Case Reports, Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Gentamicins
Topics
  • Cat-Scratch Disease (diagnosis, drug therapy)
  • Child
  • Child, Preschool
  • Female
  • Gentamicins (administration & dosage, therapeutic use)
  • Humans
  • Injections, Intravenous

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: