[Not Available].

Abstract

The purpose of this paper is to examine the eventual benefits of treatment with calcium channel blockers in post-myocardial infarction, through an overview of main placebo-controlled trials that have been conducted to test this therapeutic in acute coronary syndromes. It appears obvious that the vast majority of these trials was conducted in the pre-reperfusion era and failed to demonstrate a reduction in mortality. To conclude, the superiority of a therapy with calcium antagonists over a placebo in the management of post-myocardial infarction remains unknown. In contrast, adverse effects associated with the prescription of calcium antagonists are well known.

• Authors: Pierre-Vladimir Ennezat, Jean-Luc Auffray, Julie Darchis, Maxime Ronsselle, Xavier Gonin, Jean-Marc Aubert, Jean-Jacques Bauchart, Christophe Bauters, Eric Van Belle, Philippe Asseman
• Journal: Therapie (Therapie) 2006 May-Jun Vol. 61 Issue 3 Pg. 191-4 ISSN: 0040-5957 [Print] France
• Vernacular Title: Quelle est la place des inhibiteurs calciques lorsque les bêta-bloquants sont contre-indiqués dans le traitement du post-infarctus du myocarde ?
• PMID: 27393522 (Publication Type: English Abstract, Journal Article)
• Copyright: Copyright © 2006 Société Française de Pharmacologie et de Thérapeutique. Publié par Elsevier Masson SAS.