Abstract |
Herpesvirus of turkeys (HVT) is a widely used vector for poultry vaccines. However, different HVTs expressing different foreign antigens cannot always be used simultaneously because of the risk of recombination and interference. In this study, we inoculated a mixture of an HVT-expressing the antigen of Newcastle disease virus (NDV; HVT/ND) and Marek's disease virus (MDV) serotype 1 Rispens virus expressing the antigen of infectious bursal disease virus (IBD; Ripens/IBD) into chickens. This mixture showed 94%, 100%, or 94% protection against MDV, IBDV, or NDV challenge, respectively. In conclusion, the combination of Rispens/IBD and HVT/ND is effective for vaccination against MDV, IBDV, and NDV without significant interference.
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Authors | Yukari Ishihara, Motoyuki Esaki, Shuji Saitoh, Atsushi Yasuda |
Journal | Avian diseases
(Avian Dis)
Vol. 60
Issue 2
Pg. 473-9
(06 2016)
ISSN: 1938-4351 [Electronic] United States |
PMID | 27309290
(Publication Type: Journal Article)
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Chemical References |
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Topics |
- Animals
- Birnaviridae Infections
(prevention & control, veterinary, virology)
- Chickens
- Herpesvirus 1, Meleagrid
(immunology)
- Infectious bursal disease virus
(immunology)
- Marek Disease
(prevention & control)
- Marek Disease Vaccines
(immunology)
- Newcastle Disease
(prevention & control, virology)
- Newcastle disease virus
(immunology)
- Poultry Diseases
(prevention & control, virology)
- Vaccination
(veterinary)
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