Abstract |
We have experienced treating 29 patients of esophageal carcinoma with multiple fractions per day (MFD) examined the effectiveness of this method. A dose of 2.0 Gy was delivered to the conventional field and 1.1, 1.15, or 1.2 Gy to the gross disease at 4- to 6- hour interval for 20 days, 4 days per week. The total tumor doses were 62, 63 or 64 Gy/40 f/5 w. The following results were obtained: 1) CR rates were 44.8% on barium examination and 55.2% by endoscopic evaluation; 2) the two-year actuarial, loco-control, and disease-free survival were 49.7%, 75.5%, and 52.3%, respectively; and, 3) the acute complications were tolerable, though esophageal stricture was found to have increased in patients treated with 64 Gy.
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Authors | S Nishino, Y Kikuchi, G Sekizawa, S Matsuoka, Y Saito, K Amou, Y Uekita |
Journal | Gan no rinsho. Japan journal of cancer clinics
(Gan No Rinsho)
Vol. 35
Issue 6
Pg. 659-63
(May 1989)
ISSN: 0021-4949 [Print] Japan |
PMID | 2724545
(Publication Type: English Abstract, Journal Article)
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Topics |
- Actuarial Analysis
- Aged
- Esophageal Neoplasms
(mortality, radiotherapy)
- Esophageal Stenosis
(etiology)
- Evaluation Studies as Topic
- Female
- Humans
- Male
- Methods
- Middle Aged
- Radiation Injuries
- Radiotherapy Dosage
- Remission Induction
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