| Abstract | We examined changes in P wave height in lead II of electrocardiogram during progressive exercise in patients with chronic obstructive pulmonary disease (COPD), and obtained the slope (delta P/delta VO2, %/ml/min) of the regression line calculated from the relationship between percent change of P wave height and oxygen consumption (VO2). Four COPD patients, who had a decrease over 5 mmHg in arterial oxygen tension (PaO2) at maximal exercise (group A), had significantly greater slope (0.45 +/- 0.14%/ml/min, mean +/- S.E.) than in five COPD patients (group B, 0.14 +/- 0.05), who did not have a decrease over 5 mmHg in PaO2 at maximal exercise. The increase in P wave height during exercise was inhibited by oxygen inhalation at the given VO2 in group A. These findings suggest that increase in P wave height during exercise in COPD patients may be correlated with hypoxemia during exercise. |
| Authors | W Hida, O Taguchi, N Iwase, M Sato, T Chonan, Y Kikuchi, M Ogata, K Shirato, T Takishima
(Affiliation: First Department of Internal Medicine, Tohoku University School of Medicine, Sendai Japan.)
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| Journal | The Tohoku journal of experimental medicine
(Tohoku J Exp Med)
Vol. 157
Issue 1
Pg. 79-80
(Jan 1989)
ISSN: 0040-8727 JAPAN |
| PMID | 2711379
(Publication Type: Journal Article)
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| Topics |
- Adult
- Aged
- Electrocardiography
- Heart
(physiopathology)
- Humans
- Lung Diseases, Obstructive
(physiopathology)
- Middle Aged
- Physical Exertion
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