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Neuropathy in a patient with McArdle's syndrome and diabetes mellitus.

Abstract
A juvenile-type diabetic patient of five years standing presented with a mononeuritis and gave a history of painful muscle swelling induced by exertion. Failure of the blood lactate to rise during ischaemic exercise and a normal blood glucose rise following intravenous glucagon confirmed the clinical diagnosis of muscle glycogenosis. The association of diabetes and McArdle's Syndrome has not previously been documented. An ulnar nerve palsy, which persisted for many months, followed the ischaemic exercise test possibly due to compression by muscular swelling, but may have been exacerbated by the co-existing diabetes.
AuthorsT J Davies, J S Harrop, J M Smith, V Marks
JournalHormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme (Horm Metab Res) Vol. 9 Issue 5 Pg. 351-3 (Sep 1977) ISSN: 0018-5043 [Print] Germany
PMID270456 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Blood Glucose
  • Isoenzymes
  • Lactates
  • L-Lactate Dehydrogenase
Topics
  • Adult
  • Blood Glucose (metabolism)
  • Diabetic Neuropathies (diagnosis)
  • Glycogen Storage Disease (diagnosis)
  • Glycogen Storage Disease Type V (diagnosis)
  • Humans
  • Isoenzymes
  • Isometric Contraction
  • L-Lactate Dehydrogenase (blood)
  • Lactates (blood)
  • Male

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