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Bronchiectasis in acute leukaemia.

Abstract
Five children in remission from acute lymphoblastic leukaemia developed bronchiectasis when on chemotherapy. Persistent collapse or consolidation on chest radiographs was helpful in suggesting the diagnosis. Necropsy established the diagnosis in one child who died of massive haemoptysis when in complete remission, and bronchography confirmed the diagnosis in three. In a further child the diagnosis was based on clinical and chest X-ray findings alone. The surviving children were treated with prophylactic rotating antibiotics. Routine chest radiographs are recommended in children with acute lymphoblastic leukaemia, as bronchiectasis may otherwise be underdiagnosed.
AuthorsP J Kearney, C R Kershaw, P A Stevenson
JournalBritish medical journal (Br Med J) Vol. 2 Issue 6091 Pg. 857-9 (Oct 01 1977) ISSN: 0007-1447 [Print] England
PMID270386 (Publication Type: Case Reports, Journal Article)
Topics
  • Bronchiectasis (diagnosis, drug therapy, etiology)
  • Child, Preschool
  • Drug Therapy, Combination
  • Female
  • Humans
  • Leukemia, Lymphoid (complications, drug therapy)
  • Male
  • Remission, Spontaneous
  • Respiratory Tract Infections (complications)

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