[Iopromide 370 in coronaroventriculography, versus ioxaglate 320 mg/ml].

Abstract

Twenty-four patients with angina were included in a prospective randomized trial, comparing a new non-ionic contrast medium--iopromide 370 mgI/ml--versus the ionic low osmolar contrast medium, ioxaglate 320 mgI/ml. Twelve received iopromide 370 and twelve ioxaglate 320 mgI/ml. The main topic of this study was general and cardiac safety. Cardiac safety was monitored by EKG and diastolic and systolic blood pressures. In spite of a bias--5 patients with iopromide 370 had myocardial infarction, versus one with ioxaglate 320--there were fewer adverse effects with iopromide 370. The population of only 24 failed to reveal a statistically significant difference, but the tendency was confirmed by the meta-analysis of this multicentric study.

• Authors: H Petitier
• Journal: Annales de radiologie (Ann Radiol (Paris)) Vol. 32 Issue 4 Pt 2 Pg. 333-5 ( 1989) ISSN: 0003-4185 [Print] France
• Vernacular Title: Etude de l'iopromide 370 en coronaroventriculographie, versus ioxaglate 320 mgI/ml.
• PMID: 2688529 (Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial)

Chemical References

• Contrast Media
• Iohexol
• iopromide
• Ioxaglic Acid

Topics

• Angiocardiography
• Contrast Media
• Coronary Disease (diagnostic imaging)
• Double-Blind Method
• Female
• Humans
• Iohexol (adverse effects)
• Ioxaglic Acid (adverse effects)
• Male
• Middle Aged
• Randomized Controlled Trials as Topic