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Human pegivirus detected in a patient with severe encephalitis using a metagenomic pan-virus array.

Abstract
We have used a metagenomic microarray to detect genomic RNA from human pegivirus in serum and cerebrospinal fluid from a patient suffering from severe encephalitis. No other pathogen was detected. HPgV in cerebrospinal fluid during encephalitis has never been reported before and its prevalence in cerebrospinal fluid needs further investigation.
AuthorsHelena Fridholm, Line Østergaard Sørensen, Maiken W Rosenstierne, Henrik Nielsen, Finn Sellebjerg, Åse Bengård Andersen, Anders Fomsgaard
JournalJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology (J Clin Virol) Vol. 77 Pg. 5-8 (Apr 2016) ISSN: 1873-5967 [Electronic] Netherlands
PMID26872326 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't, Review)
CopyrightCopyright © 2016 Elsevier B.V. All rights reserved.
Topics
  • Adult
  • Encephalitis, Viral (diagnosis, virology)
  • Female
  • Flaviviridae (classification, genetics)
  • Humans
  • Metagenomics (methods)
  • Real-Time Polymerase Chain Reaction
  • Serologic Tests

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