Abstract | INTRODUCTION: MATERIAL AND METHODS: A total of 50 patients with symptomatic urethral stricture were evaluated by clinical history, physical examination, uroflowmetry and retrograde urethrogram preoperatively. All patients were treated with holmium laser urethrotomy, followed by injection of tetra-inject at the urethrotomy site. Tetra-inject was prepared by diluting acombination of 40 mg Triamcinolone, 2 mg Mitomycin, 3000 UHyaluronidase and 600 mg N-acetyl cysteine in 5-10 ml of saline, according to the stricture length. An indwelling 18 Fr silicone catheter was left in place for 7-10 days.All patients were followed-up for 6-18 months postoperatively by history, uroflowmetry, and if required, retrograde urethrogram and micturating urethrogram every 3 months. RESULTS: 41 (82%) patients had asuccessful outcome,whereas 9 (18%) had recurrences during a follow-up ranging from 6-18 months. In <1 cm length strictures, the success rate was 100%, while in 1-3 cm and >3 cm lengthsthe success rates were 81.2% and 66.7% respectively. This modality, thus, has an encouraging success rate, especially in those with short segment urethral strictures (<3 cm). CONCLUSIONS:
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Authors | Santosh Kumar, Lalit Kishore, Aditya Prakash Sharma, Nitin Garg, Shrawan Kumar Singh |
Journal | Central European journal of urology
(Cent European J Urol)
Vol. 68
Issue 4
Pg. 462-5
( 2015)
ISSN: 2080-4806 [Print] Poland |
PMID | 26855803
(Publication Type: Journal Article)
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