Descriptive study of 896 Oral squamous cell carcinomas from the only University based Oral Pathology Diagnostic Service in Sri Lanka.

Abstract

BACKGROUND:

The main objective of this study was to describe selected clinico-pathological characteristics of Oral Squamous Cell Carcinoma (OSCC) in Sri-Lanka.

MATERIALS & METHODS:

The study sample comprised of eight hundred and ninety six biopsies diagnosed as OSCC. The clinical and histopathological features were analyzed using the Chi-square test.

RESULTS:

Of the 896 biopsies, 801 were primary OSCCs, while 95 were recurrent OSCCs. Majority of the patients (78 %) were in the 5(th) to 7(th) decades of life and showed a male predilection. The buccal mucosa was the commonest site of primary OSCC comprising of 43 % of the sample. Of the primary OSCCs, with known TNM stage, 86 % were in stage 3&4 and majority (59 %) of stage 4 tumours showed tumour at one or more excision margins. Of the recurrent OSCC, 46 % developed their recurrences within one year of the excision of the primary tumour.

CONCLUSION:

In Sri-Lanka, OSCC is a major problem. Only half the patients had completely excised tumours (with clearance of >5 mm at all excision margins) at operation, and recurrences appeared early. This data should be considered in the future management policy of OSCC in Sri-Lanka.

• Authors: Primali Rukmal Jayasooriya, Thushara Nilmini Pitakotuwage, Balapuwaduge Ranjit Rigorbert Nihal Mendis, Tommaso Lombardi
• Journal: BMC oral health (BMC Oral Health) Vol. 16 Pg. 1 (Jan 08 2016) ISSN: 1472-6831 [Electronic] England
• PMID: 26745890 (Publication Type: Journal Article)

Topics

• Carcinoma, Squamous Cell (diagnosis, pathology)
• Diagnostic Services
• Female
• Humans
• Male
• Mouth Neoplasms (diagnosis, pathology)
• Neoplasm Recurrence, Local
• Pathology, Oral
• Sri Lanka
• Universities