Pulmonary surfactant: physiology, pharmacology and clinical uses.

Abstract

The endogenous surfactant system in the lungs is complex. The synthetic, recycling and metabolic pathways are clear but the controlling mechanisms are not fully understood. Surfactant-specific proteins are important and their isolation and manufacture opens up new prospects for production of a synthetic surfactant with all the properties of natural human surfactant for therapy and prophylaxis of neonatal respiratory distress syndrome.

• Authors: N S Morton
• Journal: British journal of hospital medicine (Br J Hosp Med) Vol. 42 Issue 1 Pg. 52-8 (Jul 1989) ISSN: 0007-1064 [Print] England
• PMID: 2673470 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)

Chemical References

• Pulmonary Surfactants

Topics

• Humans
• Infant, Newborn
• Pulmonary Surfactants (pharmacology, therapeutic use)
• Respiratory Distress Syndrome, Newborn (drug therapy)