Abstract | OBJECTIVE: METHODS: The mRNA and protein expressions of TPX2 in breast cancer tissue and cell lines were assessed by quantitative RT-PCR and Western blot. The effect of TPX2 with RNA interference on proliferation, invasion and migration of breast cancer cells was observed by MTT and Transwell assays. RESULTS: CONCLUSIONS: Significantly upregulated TPX2 expression is observed in breast cancer tissue and cells, and contributes to promote the proliferation, migration and invasion of breast cancer cells.
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Authors | Yong Yang, Da-Peng Li, Na Shen, Xiao-Cheng Yu, Jie-Bao Li, Qi Song, Jia-Heng Zhang |
Journal | Asian Pacific journal of tropical medicine
(Asian Pac J Trop Med)
Vol. 8
Issue 12
Pg. 1064-1070
(Dec 2015)
ISSN: 2352-4146 [Electronic] India |
PMID | 26706681
(Publication Type: Journal Article)
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Copyright | Copyright © 2015 Hainan Medical College. Production and hosting by Elsevier B.V. All rights reserved. |