Bilateral renal agenesis and Mullerian anomalies in a 47,XXX fetus.

Abstract

Congenital absence of the kidneys (bilateral renal agenesis, BRA) is a genetically heterogeneous condition, and all modes of inheritance have been suggested as causes. The finding of a 47,XXX chromosome constitution in a fetus with BRA and developmental arrest of the mesonephric and paramesonephric systems raises the possibility that X chromosome trisomy also may cause the urogenital adysplasia sequence.

• Authors: W A Hogge, D J Vick, P A Schnatterly, R H MacMillan
• Journal: American journal of medical genetics (Am J Med Genet) Vol. 33 Issue 2 Pg. 242-3 (Jun 1989) ISSN: 0148-7299 [Print] United States
• PMID: 2669483 (Publication Type: Case Reports, Journal Article)

Topics

• Adult
• Female
• Fetal Diseases (genetics)
• Genetic Counseling
• Humans
• Kidney (abnormalities)
• Mullerian Ducts (pathology)
• Pregnancy
• Prenatal Diagnosis
• Trisomy
• Ultrasonography
• X Chromosome