Abstract |
Venous thromboembolism (VTE) is a potential complication occurring after total knee arthroplasty (TKA). We investigated the incidence of VTE after TKA using contrast-enhanced computed tomography (CT), and assessed the efficacy of VTE prophylaxis ( fondaparinux and enoxaparin). At our hospital, 189 patients (225 knees) underwent TKA between April 2007 and October 2011. The 225 knees were divided into a control group with no VTE prophylaxis (31 cases), a fondaparinux group (107 cases), and an enoxaparin group (87 cases). Contrast-enhanced CT screening for VTE was performed in all cases on day 5 or 6 after TKA. D-dimer levels were measured on day 5 after TKA, and were significantly lower in the fondaparinux (9.8 ± 3.8) and enoxaparin groups (9.4 ± 4.9) than in the control group (15.6 ± 9.8) (p < 0.001). However, no statistically significant difference in the incidence of VTE was observed among the groups (control, 61.3%; fondaparinux, 49.5%; enoxaparin, 50.6%). Prophylaxis was not effective for the prevention of VTE as detected by contrast-enhanced CT after TKA. CT should be performed after TKA, even when VTE prophylaxis is used.
|
Authors | Yukimasa Okada, Takayuki Furumatsu, Shinichi Miyazawa, Takaaki Tanaka, Masataka Fujii, Toshifumi Ozaki, Nobuhiro Abe |
Journal | Acta medica Okayama
(Acta Med Okayama)
Vol. 69
Issue 6
Pg. 355-9
( 2015)
ISSN: 0386-300X [Print] Japan |
PMID | 26690246
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Chemical References |
|
Topics |
- Aged
- Arthroplasty, Replacement, Knee
(adverse effects)
- Contrast Media
- Female
- Humans
- Male
- Middle Aged
- Radiographic Image Enhancement
- Tomography, X-Ray Computed
(methods)
- Venous Thromboembolism
(diagnostic imaging, prevention & control)
|