Erythrocyte insulin binding in a family with hereditary motor sensory neuropathy (Charcot-Marie-Tooth) with superimposed insulin-dependent type I diabetes mellitus.

Abstract

Studies on erythrocyte insulin receptors were performed in a family with hereditary motor sensory neuropathy (Charcot-Marie-Tooth) with superimposed type I diabetes mellitus. The maximum specific insulin binding of the erythrocytes was high and the increase was shown to be due to increased affinity of the insulin receptor to erythrocytes.

• Authors: S A Ivarsson, I Bjerre
• Journal: Diabetes research (Edinburgh, Scotland) (Diabetes Res) Vol. 10 Issue 1 Pg. 49-51 (Jan 1989) ISSN: 0265-5985 [Print] Scotland
• PMID: 2667841 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• C-Peptide
• Insulin
• Receptor, Insulin

Topics

• Adolescent
• Adult
• Aged
• C-Peptide (blood)
• Charcot-Marie-Tooth Disease (blood, complications, genetics)
• Diabetes Mellitus, Type 1 (blood, complications, genetics)
• Erythrocytes (metabolism)
• Female
• Humans
• Insulin (blood)
• Muscular Atrophy, Spinal (blood)
• Receptor, Insulin (metabolism)
• Reference Values