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Malignant degeneration of rectal endometriosis.

AbstractBACKGROUND:
Endometriosis is a relatively common disease among women with child-bearing potential, and rare before puberty or following menopause. It consists of the presence of hormone-responsive endometrium outside the endometrial cavity.
CASE REPORT:
We report the case of a patient with a rectal lesion, initially approached as a primary rectal malignancy, where histopathology eventually revealed an adenocarcinoma arising from endometrial tissue in the colonic wall.
DISCUSSION:
Endometriosis has an estimated rated of 10-20%. Sites may be split up into two larger categories - gonadal and extragonadal. The frequency of extragonadal endometriosis in the bowel is estimated to involve 3%-37% of women with pelvic endometriosis, and most lesions are found in the sigmoid colon and rectum. The malignant transformation of endometriotic lesions is estimated between 0.3% and 1% of cases. The gold standard in the diagnosis of intestinal endometriosis is exploratory laparotomy and the pathological study of specimens. Adjuvant radiotherapy and chemotherapy, although used for some patients, have not proven effective.
AuthorsJosé Andrés García-Marín, Enrique Manuel Pellicer-Franco, Victoriano Soria-Aledo, Mónica Mengual-Ballester, Graciela Valero-Navarro, José Luis Aguayo-Albasini
JournalRevista espanola de enfermedades digestivas : organo oficial de la Sociedad Espanola de Patologia Digestiva (Rev Esp Enferm Dig) Vol. 107 Issue 12 Pg. 761-3 (Dec 2015) ISSN: 1130-0108 [Print] Spain
PMID26671590 (Publication Type: Case Reports, Journal Article)
Topics
  • Adenocarcinoma (pathology)
  • Cell Transformation, Neoplastic
  • Colonic Diseases (pathology)
  • Endometriosis (pathology)
  • Female
  • Humans
  • Middle Aged
  • Precancerous Conditions (pathology)
  • Rectal Neoplasms (pathology)

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