Early bilateral nephrectomy in infantile autosomal recessive polycystic kidney disease.

Abstract

The management of neonatal autosomal recessive polycystic kidney disease (ARPKD) complicated by severe pulmonary insufficiency presents complex clinical challenges. Where massive nephromegaly exists, early bilateral nephrectomy, supportive peritoneal dialysis and early aggressive nutrition can minimise infant mortality. Consensus, however, is lacking on the role and optimal timing of nephrectomy, with decision-making driven by the patient's clinical condition and the expertise of the centre. We report on our experience of an infant with ARPKD requiring neonatal renal replacement therapy and survival at 14 months following early bilateral nephrectomy.

• Authors: Tamara Mary Mallett, Emma O'Hagan, Karl Gerard McKeever
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Dec 15 2015) ISSN: 1757-790X [Electronic] England
• PMID: 26670891 (Publication Type: Case Reports, Journal Article)
• Copyright: 2015 BMJ Publishing Group Ltd.

Topics

• Echocardiography
• Female
• Follow-Up Studies
• Humans
• Infant
• Male
• Nephrectomy (methods)
• Peritoneal Dialysis (methods)
• Polycystic Kidney, Autosomal Recessive (diagnosis, surgery)
• Pregnancy
• Treatment Outcome