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Endocarditis due to Citrobacter diversus developing resistance to cephalothin.

Abstract
A 43-year-old man was admitted with acute bacterial endocarditis. Citrobacter diversus susceptible to cephalothin was isolated from blood cultures. Citrobacter diversus was later isolated from the aortic valve cusps at surgery, but this isolate was resistant to cephalothin. Laboratory testing showed that the Citrobacter diversus recovered from blood cultures was capable of producing mutants highly resistant to cephalothin.
AuthorsD MacCulloch, R Menzies, B M Cornere
JournalThe New Zealand medical journal (N Z Med J) Vol. 85 Issue 583 Pg. 182-3 (Mar 09 1977) ISSN: 0028-8446 [Print] New Zealand
PMID266661 (Publication Type: Journal Article)
Chemical References
  • Cephalothin
Topics
  • Adult
  • Cephalothin (therapeutic use)
  • Citrobacter
  • Drug Resistance, Microbial
  • Endocarditis, Bacterial (drug therapy)
  • Enterobacteriaceae Infections (drug therapy)
  • Female
  • Humans
  • Male

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