Abstract |
1 Labetalol was given to 41 hypertensive patients in a divided dosage of 150-2,400 mg daily for periods ranging from 1-64 months. 2 Monotherapy with labetalol was adequate in 12 out of 19 patients with essential hypertension and in 15 out of the 22 with renal hypertension. 3 Following a single dose of labetalol 200 mg orally a hypotensive response was seen between 1.5 and 2 hours. 4 In the doses used there was no exercise or postural hypotension. 5 No reduction in overall renal function attributable to labetalol was seen.
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Authors | F D Thompson, A M Joekes, M M Hussein |
Journal | British journal of clinical pharmacology
(Br J Clin Pharmacol)
Vol. 8 Suppl 2
Pg. 129S-33S
(Apr 1979)
ISSN: 0306-5251 [Print] England |
PMID | 26635153
(Publication Type: Journal Article)
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Copyright | 1979 The British Pharmacological Society. |