Live kidney donation from a person with haemophilia.

Abstract

There are many documented cases of a person with haemophilia successfully receiving a solid organ transplant, including liver and kidney. However, there is no literature reporting live organ donation by a person with haemophilia. Presumably, this is because the associated risks of excessive bleeding, inhibitor development after a period of intensive treatment with factor replacement and the possibility of variant Creutzfeldt-Jakob disease transmission in those previously treated with blood products, are considered excessive. This case describes a 24-year-old man who was diagnosed with mild haemophilia A during his pretransplant work up as a potential live kidney donor to his sister. He then went on to successfully donate his kidney, without complications. To the best of our knowledge, this is the first description of a person with haemophilia being a living organ donor.

• Authors: Christopher McCauley, Agnes Masengu, Aisling E Courtney, Gary Benson
• Journal: BMJ case reports (BMJ Case Rep) Vol. 2015 (Dec 01 2015) ISSN: 1757-790X [Electronic] England
• PMID: 26628308 (Publication Type: Case Reports, Journal Article)
• Copyright: 2015 BMJ Publishing Group Ltd.

Chemical References

• Hemostatics
• Factor VIII
• Deamino Arginine Vasopressin

Topics

• Adult
• Deamino Arginine Vasopressin (blood, therapeutic use)
• Factor VIII (drug effects)
• Hemophilia A (blood, surgery)
• Hemostatics (blood, therapeutic use)
• Humans
• Kidney Transplantation
• Living Donors
• Male
• Tissue and Organ Harvesting
• Young Adult