Dehydration of Aldoximes Using PhSe(O)OH as the Pre-Catalyst in Air.

Abstract

PhSe(O)OH was found to be a good pre-catalyst for aldoxime dehydrations in open air. Compared with the previously reported (PhSe)(2)-H(2)O(2) system, it is more stable and milder, affording broader application scopes due to a higher functional group tolerance. The control experiments for mechanism study disclosed that air was the key factor for the reaction to maintain enough concentration of PhSeOH, which should be the real catalytic species.

• Authors: Xu Zhang, Jingjing Sun, Yuanhua Ding, Lei Yu
• Journal: Organic letters (Org Lett) Vol. 17 Issue 23 Pg. 5840-2 (Dec 04 2015) ISSN: 1523-7052 [Electronic] United States
• PMID: 26574922 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Organoselenium Compounds
• Oximes
• Hydrogen Peroxide
• acetaldehyde oxime

Topics

• Air
• Catalysis
• Dehydration
• Hydrogen Peroxide
• Molecular Structure
• Organoselenium Compounds (chemistry)
• Oximes (chemistry)