Cutaneous leishmaniasis mimicking granulomatous cheilitis and treated successfully with oral fluconazole in a boy.

Abstract

Cutaneous leishmaniasis is a protozoan infectious disease and widespread in Mediterranean basin including Turkey. Lesions usually start with erythematous papules, gradually enlarges and afterwards it ulcerates. We present a 12-year-old boy with diffuse persistent lip swelling mimicking granulomatous cheilitis. Systemic glucantime was started. However, severe hypotension and bradycardia was developed after injection. Oral fluconazole was started and the lesion resolved completely. Cutaneous leishmaniasis can have varied clinical manifestations and should be suspected especially in endemic areas. Oral fluconazole seems to be safe and effective treatment modality in paediatric cases.

• Authors: Gamze Serarslan, Metin Aksakal
• Journal: Annals of parasitology (Ann Parasitol) Vol. 61 Issue 3 Pg. 197-9 ( 2015) ISSN: 2299-0631 [Print] Poland
• PMID: 26568994 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiprotozoal Agents
• Organometallic Compounds
• Meglumine
• Meglumine Antimoniate
• Fluconazole

Topics

• Antiprotozoal Agents (adverse effects, therapeutic use)
• Child
• Diagnosis, Differential
• Fluconazole (therapeutic use)
• Humans
• Leishmaniasis, Cutaneous (diagnosis, drug therapy)
• Lip (pathology)
• Male
• Meglumine (adverse effects, therapeutic use)
• Meglumine Antimoniate
• Melkersson-Rosenthal Syndrome (diagnosis)
• Organometallic Compounds (adverse effects, therapeutic use)
• Treatment Outcome