Abstract | OBJECTIVE: METHODS: Levels of amyloid protein β (Aβ42, Aβ40) and phosphorylated Tau-protein (P-tau) in CSF and ratio of Aβ42/Aβ40 were tested in 5 cases with CAA dementia and 20 cases with Alzheimer's disease collected at Peking Union Medical College Hospital from December 2001 to March 2011. RESULTS: The levels of Aβ42, Aβ40, and P-tau in CSF and ratio of Aβ42/Aβ40 were (660.4 ± 265.2) ng/L, (7111.0 ± 1033.4) ng/L, (71.8 ± 51.5) ng/L, and 0.077 ± 0.033, respectively in CAA dementia and (663.6 ± 365.6) ng/L, (5115.0 ± 2931.1) ng/L, (47.7 ± 38.8) ng/L, and 0.192 ± 0.140, respectively in Alzheimer's disease patients. There were no statistically significant differences between CAA dementia and Alzheimer's disease in terms of these CSF biomarkers (all P>0.05). CONCLUSION:
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Authors | Yan-feng Li, Fang-fang Ge, Yong Zhang, Hui You, Zhen-xin Zhang |
Journal | Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih
(Chin Med Sci J)
Vol. 30
Issue 3
Pg. 170-3
(Sep 2015)
ISSN: 1001-9294 [Print] China |
PMID | 26564416
(Publication Type: Journal Article)
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Chemical References |
- Amyloid beta-Peptides
- Apolipoproteins E
- Biomarkers
- tau Proteins
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Topics |
- Aged
- Aged, 80 and over
- Amyloid beta-Peptides
(cerebrospinal fluid)
- Apolipoproteins E
(genetics)
- Biomarkers
(cerebrospinal fluid)
- Cerebral Amyloid Angiopathy
(cerebrospinal fluid)
- Dementia
(cerebrospinal fluid)
- Humans
- Male
- tau Proteins
(cerebrospinal fluid)
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