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Analysis of the healing process of the wounds occurring in rats using laser therapy in association with hydrocolloid.

AbstractPURPOSE:
To evaluate wound healing in rats by using low-level laser therapy (LLLT) associated with hydrocolloid occlusive dressing.
METHODS:
Forty male, adult, Wistar rats were used, distributed into four groups: LG (received 2 J/cm² of laser therapy); HG (treated with hydrocolloid); LHG (treated with 2 J/cm² of laser therapy and hydrocolloid); and the CG (treated with 1 mL of 0.9% saline). The wound was evaluated at pre-determined periods 3rd and 7th days, considering the macroscopic and histological parameters (inflammatory cells, capillary neoformation, fibroblasts, collagen formation and reepithelialization).
RESULTS:
The LG group at seven days showed increased collagen formation, the LHG group at 3 days showed mild collagen formation. The HG group and the CG at 7 days showed complete reepithelialization.
CONCLUSION:
Low-level laser therapy as well as the hydrocolloid dressing have favored the wound-healing process in rats.
AuthorsShirley Santos Martins, Orlando Jorge Martins Torres, Orlando José dos Santos, Francisco de Assis Limeira Júnior, Euler Nicolau Sauaia Filho, Syomara Pereira da Costa Melo, Rayan Haquim Pinheiro Santos, Vivian Brito Silva
JournalActa cirurgica brasileira (Acta Cir Bras) Vol. 30 Issue 10 Pg. 681-5 (Oct 2015) ISSN: 1678-2674 [Electronic] Brazil
PMID26560426 (Publication Type: Evaluation Study, Journal Article, Research Support, Non-U.S. Gov't)
Chemical References
  • Collagen
Topics
  • Animals
  • Bandages, Hydrocolloid
  • Collagen (analysis, radiation effects)
  • Combined Modality Therapy
  • Fibroblasts (radiation effects)
  • Lasers, Semiconductor (therapeutic use)
  • Low-Level Light Therapy (methods)
  • Male
  • Occlusive Dressings
  • Random Allocation
  • Rats, Wistar
  • Reproducibility of Results
  • Time Factors
  • Treatment Outcome
  • Wound Healing (radiation effects)

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