Once-daily luliconazole cream 1% for the treatment of interdigital tinea pedis.

Abstract

Luliconazole is an imidazole antifungal agent with a unique chemical structure. In this article, we summarize the in vitro data, animal studies and clinical trial data relating to the use of topical luliconazole cream 1% in the treatment of tinea pedis. Preclinical studies have demonstrated potent activity against dermatophytes. Luliconazole has strong fungicidal activity against Trichophyton spp., similar to that seen with terbinafine. Evidence from clinical trials in tinea pedis have shown once-daily application of luliconazole cream 1% for 14 days to be effective and well tolerated.

• Authors: Michael H Gold, Jason T Olin
• Journal: Expert review of anti-infective therapy (Expert Rev Anti Infect Ther) Vol. 13 Issue 12 Pg. 1433-40 ( 2015) ISSN: 1744-8336 [Electronic] England
• PMID: 26559086 (Publication Type: Journal Article, Review)

Chemical References

• Antifungal Agents
• Imidazoles
• luliconazole

Topics

• Administration, Cutaneous
• Animals
• Antifungal Agents (administration & dosage)
• Clinical Trials as Topic (methods)
• Drug Administration Schedule
• Drug Evaluation, Preclinical (methods)
• Humans
• Imidazoles (administration & dosage)
• Tinea Pedis (diagnosis, drug therapy)
• Treatment Outcome